The cells lining the bladder and urinary tract can begin to grow in an uncontrolled manner. Transitional cells which line the bladder wall are subject to this uncontrolled growth, which results in bladder cancer.

Transitional Cell Carcinoma (TCC) is the most common malignancy of the urinary tract in dogs.

Although the actual incidence is low, there has been a 250% increase in cases over the past 10 years.

TCC has a poor prognosis because it is usually diagnosed when the disease is quite advanced and therapy is less successful.

 

Most cases occur in dogs more than 7 years old. Females and overweight dogs appear to be at higher risk.

 

Diagnosis is complicated by clinical signs which mimic urinary tract infections. Such signs and symptoms include:

 

• Hematuria - Brown color or blood in the urine

• Pollakiuria -  Frequent urination, usually in small amounts

• Dysuria - Difficult or painful urination

• Poor response to antibiotics

 

The V-BTA test is highly sensitive for the detection of TCC in the urinary tract, including the bladder, urethra, and prostate. The V-BTA test is suggested as a practical screening test to rule out TCC in older dogs or patients with clinical signs related to the urinary tract.

 

Treatments are far more effective for early-stage disease. Current treatments include: 

 

• Surgical Resection

• Radiation

• Chemotherapy

• Non-steroidal anti-inflammatory drugs